Serum Proteins: A Review.
نویسندگان
چکیده
For many years it has been realized that ser globulin is not a single homogeneous protein, comprises a variety of proteins which have 4 ferent physical, chemical, and physiological p perties. The salt fractionation methods that h been 'used for many years do not yield fracti which are sharply distinguished one from anot in any properties. A striking example is that the fractionation of diphtheria antitoxic ser with ammonium sulphate; antitoxin is found a series of fractions ranging from that precipita between 30 and 35% saturation to that E cipitated between 52 and 56% saturation (E and Glennie, 1931). During recent years new methods have b used for the separation and study of the E teins of serum and plasma. In particular moving boundary method of electrophoretic an: sis developed by Tiselius (1937) raised great hol for by this method at least five fractions of ( ferent mobility can be recognized in human seru the mobilities of these fractions are distinct E little material of intermediate mobility can 0* 161 IV. Composition, Physical, and Physiological Properties ... ... ... ... 168 162 Composition Molecular Weights Immunology 163 Physiological Properties V. Serum Proteins in Disease ... 173 Response to Injury and Infection Effect of Deficiency of Protein Lipaemia Liver Disease Myelomatosis Miscellaneous Diseases 167 Other Abnormal Proteins
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ورودعنوان ژورنال:
- Journal of clinical pathology
دوره 2 3 شماره
صفحات -
تاریخ انتشار 1949